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CKB Drug Classes
[
A
,
B
,
C
,
D
,
E
,
F
,
G
,
H
,
I
,
J
,
K
,
L
,
M
,
N
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O
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P
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R
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S
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T
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U
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V
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W
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Y
]
A
ABL Inhibitor (pan)
9
ABL1 Inhibitor
8
Adenosine Targeting
23
Akt Inhibitor (Pan)
21
AKT Inhibitor (Pan) - ATP competitive
7
Akt1 Inhibitor
7
Akt2 Inhibitor
2
ALK Inhibitor
32
Antibiotic Antineoplastic
1
Antifungal Agent
1
Antimicrotubule Agent
14
Antisense Therapy
14
Aromatase Inhibitor
3
ATM Inhibitor
13
ATR Inhibitor
16
AURK Inhibitor (Pan)
12
Aurka Inhibitors
27
Aurkb Inhibitors
21
Aurkc Inhibitors
3
AXL Antibody
5
AXL Inhibitor
30
B
BCL-XL inhibitor
14
BCL2 Family Inhibitor
6
BCL2 inhibitor
27
BCL6 Inhibitor
6
BCR-ABL Inhibitor
32
BET Inhibitor (Pan)
32
BIRC5 Inhibitor
1
BRAF Inhibitor
25
BRD2 Inhibitor
1
BRD3 Inhibitor
2
BRD4 Inhibitor
9
BTK inhibitor
37
C
c-MYC Inhibitor
12
CBP/p300 inhibitor
13
CCR8 Antibody
9
CD19 Antibody
20
CD20 Antibody
24
CD22 Immune Cell Therapy
16
CD27 Antibody
3
CD276 Antibody
16
CD3 Antibody
98
CD33 Antibody
13
CD37 Antibody
8
CD38 Antibody
20
CD39 Antibody
5
CD40 Antibody
14
CD47 Antibody
31
CD73 Antibody
12
CD74 Antibody
3
CDC7 Inhibitor
4
CDK Inhibitor (Pan)
3
CDK1 Inhibitor
13
CDK2 Inhibitor
30
CDK4 Inhibitor
17
CDK4/6 Inhibitor
13
CDK5 Inhibitor
8
CDK6 Inhibitor
6
CDK7 Inhibitor
16
CDK8 Inhibitor
5
CDK9 Inhibitor
21
CEACAM5 Antibody
8
CEACAM6 Antibody
3
Chemotherapy - Alkylating
18
Chemotherapy - Anthracycline
13
Chemotherapy - Antimetabolite
14
Chemotherapy - Platinum
7
Chemotherapy - Taxane
3
CHK Inhibitor (Pan)
2
CHK1 Inhibitor
18
CHK2 Inhibitor
7
CLDN18.2 Antibody
18
CLDN6 Antibody
8
CRAF Inhibitor
12
CSF1 Antibody
2
CSF1R Antibody
5
CSF1R Inhibitor
28
CTLA4 Antibody
31
CTLA4 Inhibitor
4
CTNNB1 Inhibitor
27
CXCR Antagonist
4
CXCR4 Inhibitor
15
D
DDR1 Inhibitor
10
DDR2 inhibitor
7
DGKZ Inhibitor
3
DLL4 Antibody
7
DNA_PK Inhibitor
9
DNMT inhibitor (Pan)
5
DNMT1 inhibitor
4
DOT1L Inhibitor
3
DYRK1A Inhibitor
5
DYRK1B Inhibitor
4
E
EGFR Antibody
58
EGFR Immune Cell Therapy
4
EGFR Inhibitor (Pan)
62
EGFR Inhibitor 1st gen
3
EGFR Inhibitor 2nd gen
5
EGFR Inhibitor 3rd gen
26
EGFR Inhibitor 4th gen
15
EHMT2 Inhibitor
5
EPHB4 Inhibitor
6
ERK Inhibitor (pan)
21
ERK1 Inhibitor
2
ERK2 Inhibitor
2
EZH1 inhibitor
5
EZH2 inhibitor
20
F
FAK inhibitor
15
Farnesyltransferase Inhibitor
4
FASN Inhibitor
5
FGFR Inhibitor (Pan)
26
FGFR1 Inhibitor
28
FGFR2 Antibody
3
FGFR2 Inhibitor
23
FGFR3 Antibody
4
FGFR3 Inhibitor
19
FGFR4 Antibody
1
FGFR4 Inhibitor
9
FLT3 Antibody
5
FLT3 Inhibitor
69
FOLR1-targeted Therapy
22
G
Gamma secretase inhibitor
13
GITR Antibody
6
GLI1/2 inhibitor
6
Glutaminase Inhibitor
3
GPC3 Antibody
4
GR Antagonist
2
GSK-3alpha Inhibitor
1
GSK-3beta Inhibitor
4
GSK3 Inhibitor (Pan)
3
H
HDAC Inhibitor
45
HER inhibitor (Pan)
6
HER2 (ERBB2) Antibody
75
HER2 (ERBB2) Antibody-Drug Conjugate
30
HER2 (ERBB2) Immune Cell Therapy
6
HER2 (ERBB2) Vaccine
14
HER2 Inhibitor
42
HER3 (ERBB3) Antibody
23
HER3 Inhibitor
1
HGF Antibody
4
HIF2A Inhibitor
6
Hormone - Anti-androgens
53
Hormone - Anti-estrogens
29
Hormone - Anti-progestins
6
Hormone Antineoplastics
2
HRAS Inhibitor
1
HSP90 Inhibitor
35
I
IDH Inhibitor (Pan)
3
IDH1 Inhibitor
8
IDH2 Inhibitor
5
IDO1 Inhibitor
12
IGF-1R Inhibitor
17
IGF1/2 Antibody
2
IGF1R Antibody
8
Immune Checkpoint Inhibitor
149
IRAK1/4 Inhibitor
2
IRAK4 Inhibitor
7
J
JAK Inhibitor (Pan)
9
JAK Inhibitor (Pan) - ATP competitive
3
JAK1 Inhibitor
9
JAK1 Inhibitor - ATP competitive
5
JAK2 Inhibitor
19
JAK2 Inhibitor - ATP competitive
15
JAK3 Inhibitor
6
JAK3 Inhibitor - ATP competitive
4
JNK Inhibitor
5
K
KDM1A Inhibitor
15
KDM4 Inhibitor
4
KIT Inhibitor
57
KRAS G12C inhibitor
34
KRAS G12D Inhibitor
15
KRAS Inhibitor
17
L
LAG3 Antibody
18
LCK Inhibitor
6
LYN Inhibitor
4
M
MAP4K1 Inhibitor
7
MCL1 Inhibitor
18
MDM2 Inhibitor
23
MDM4 inhibitor
8
MEK inhibitor (Pan)
26
MEK1 Inhibitor
26
MEK2 Inhibitor
24
MEN1-KMT2A Inhibitor
8
MERTK Antibody
1
MERTK Inhibitor
13
MET Antibody
29
MET Immune Cell Therapy
1
MET Inhibitor
59
Microbiome
7
MNK1/2 Inhibitor
3
MPS1 Inhibitor
27
MSLN Antibody
11
mTOR Inhibitor
51
mTORC1 Inhibitor
9
mTORC2 Inhibitor
2
MUC16 Targeted Therapy
10
N
NAMPT Inhibitor
7
NKG2A Antibody
3
NOTCH Inhibitor (Pan)
5
NOTCH1 Antibody
2
NOTCH2 Antibody
3
NOTCH3 Antibody
2
O
OX40 Antibody
14
P
p38 MAPK Inhibitor (Pan)
3
p38-alpha Inhibitor
1
p53 Activator
11
p53 Gene Therapy
4
p53 Vaccine
5
PAK1 Inhibitor
11
PARP Inhibitor (Pan)
30
PARP-1 Inhibitor
9
PARP-2 Inhibitor
1
PD-L1 Inhibitor
13
PD-L1/PD-1 antibody
120
PDGFR Inhibitor (Pan)
30
PDGFR-alpha Inhibitor
9
PDGFR-beta Inhibitor
14
PDGFRA Antibody
2
PDK-1 Inhibitor
1
PDPK1 Inhibitor
10
PI3K Inhibitor (Pan)
41
PIK3CA inhibitor
23
PIK3CB inhibitor
8
PIK3CD inhibitor
27
PIK3CG inhibitor
10
PIM Inhibitor (Pan)
9
PIM1 Inhibitor
2
PIM3 Inhibitor
2
PKA Inhibitor
2
PKC alpha Inhibitor
6
PKC beta Inhibitor
6
PKC Inhibitor (Pan)
11
PLK1 Inhibitor
18
PP2A Activator
7
PP2A Inhibitor
2
PPM1D Inhibitor
3
PRMT5 Inhibitor
16
PSMA Antibody
20
R
RAD51 Inhibitor
4
RAF Inhibitor (Pan)
28
RAS Inhibitor (Pan)
10
RET Inhibitor
52
RON Inhibitor
11
ROR1 Antibody
7
ROS1 Inhibitor
20
S
S6 Kinase Inhibitor
5
SHP2 Inhibitor
20
SIRT1 Activator
3
SIRT1 Inhibitor
5
SIRT2 Inhibitor
5
SIRT3 Inhibitor
1
SMAC Mimetic
8
SMO Inhibitor
16
SMYD3 Inhibitor
3
SOS1 Inhibitor
14
SRC Inhibitor
31
STAT3 Inhibitor
26
STAT5 Inhibitor
4
STING1 Agonist
19
SYK Inhibitor
15
T
Tankyrase Inhibitor
11
TGFB (Pan) Antibody
5
TGFB inhibitor
5
TGFB2 Vaccine
1
TGFBR inhibitor (pan)
2
TGFBR1 inhibitor
16
TGFBR2 Antibody
3
TGFBR2 inhibitor
1
TIE2 Inhibitor
3
TIGIT Antibody
19
TIM-3 Antibody
9
TLR4 Agonist
2
TLR7 Agonist
12
TLR8 Agonist
9
TLR9 Agonist
9
TNFRSF17 Antibody
19
TNFRSF9 Antibody
31
TNK2 Inhibitor
6
TOPO Inhibitor (Pan)
3
TOPO1 inhibitor
11
TOPO2 inhibitor
5
Trk Receptor Inhibitor (Pan)
31
TrkA Receptor Inhibitor
8
TROP2 Antibody
10
TYRO3 Inhibitor
8
U
USP1 inhibitor
7
USP7 Inhibitor
4
V
VEGF Antibody
11
VEGFA Antibody
4
VEGFR Inhibitor (Pan)
36
VEGFR1 Inhibitor
6
VEGFR2 Antibody
4
VEGFR2 Immune Cell Therapy
1
VEGFR2 Inhibitor
37
VEGFR3 Antibody
1
VEGFR3 Inhibitor
6
VSIR Antibody
6
W
WEE1 Inhibitor
7
WNT Inhibitor
16
Y
YAP Inhibitor
3
YES Inhibitor
3
[
A
,
B
,
C
,
D
,
E
,
F
,
G
,
H
,
I
,
J
,
K
,
L
,
M
,
N
,
O
,
P
,
R
,
S
,
T
,
U
,
V
,
W
,
Y
]